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Critical Allergic Reactions. Promethazine/phenylephrine/codeine may perhaps lead to allergic reactions, which may be significant. Prevent having promethazine/phenylephrine/codeine and have assist right away In case you have any of the next signs of a serious allergic response.

Usually do not use with another drug that contains acetaminophen without inquiring your health practitioner or pharmacist very first. Acetaminophen is in several nonprescription and prescription prescription drugs (including agony/fever medicine or cough-and-cold items).

Plasma half-life of codeine and its metabolites happen to be documented to generally be close to three hours Label.

We'll keep on to watch this safety concern. We are thinking about additional regulatory motion with the OTC codeine products that are available in some states. OTC codeine goods can be found in combination with other medicines for cough and chilly symptoms.

Talk to your physician or pharmacist if you ought to have naloxone accessible to handle opioid overdose. Teach Your loved ones or house members concerning the signs of an opioid overdose and the way to handle it.

Tend not to consume Alcoholic beverages or use prescription or over-the-counter medicines that consist of Alcoholic beverages. Utilizing Liquor whilst using promethazine/phenylephrine/codeine can cause you to overdose and die.

It works by selectively inhibiting the enzyme COX-two, which performs a essential position during the production of prostaglandins that induce inflammation and pain. Celecoxib is most well-liked about some other NSAIDs as a consequence of its decrease risk of gastrointestinal Uncomfortable side effects which include ulcers and bleeding.

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The chance for intense respiration troubles is increased when you start this medication and following a dose increase, or if you take the incorrect dose/energy. Using this medication with alcohol or other drugs that could potentially cause drowsiness or respiratory challenges may possibly lead to pretty really serious Unintended effects, together with Demise. Also, other remedies can have an effect on the removal of codeine from the overall body, which may influence how codeine works.

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Promethazine and codeine mix is employed To ease cough, runny or stuffy nose, sneezing, or other indicators attributable to allergies or perhaps the typical chilly.

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